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  4. Is Pantothenic Acid the Energy Vitamin You Didn’t Know You Needed?

Is Pantothenic Acid the Energy Vitamin You Didn’t Know You Needed?

Feeling tired all the time? The solution might be simpler than you think: Pantothenic acid. Here’s everything you need to know about Vitamin B5.

3 MIN READ — 02/12/2025

Do you often feel exhausted, struggle with sleep issues, or feel like your mental performance could use a boost? The solution might be simpler than you think: pantothenic acid. But what exactly is it? Here, we’ll break down everything you need to know about vitamin B5—from its benefits to the best foods that provide it.

Table of Contents

  • 01.

    What is Pantothenic Acid?

  • 02.

    Pantothenic Acid: Energy for Body and Mind

  • 03.

    How Much Pantothenic Acid Do I Need?

  • 04.

    Foods High in Pantothenic Acid: The Best Sources of Vitamin B5

  • 05.

    How Can I Recognise a Pantothenic Acid Deficiency?

At a Glance

  • 01.

    Pantothenic acid, also known as vitamin B5, supports many vital functions in the body.

  • 02.

    It’s a water-soluble vitamin that helps convert food into energy, supports metabolism, and contributes to the health of skin, hair, nails, and the nervous system.

  • 03.

    Pantothenic acid is found in many foods, including eggs, nuts, whole grains, and offal. Since it’s water-soluble and heat-sensitive, it’s best to prepare these foods gently to avoid losing nutrients.

What is Pantothenic Acid?

Pantothenic acid, also known as vitamin B5, is a water-soluble vitamin. This means that any excess is excreted in your urine, making it unlikely to overdose on it. Since our bodies can’t produce pantothenic acid, we need to get it from our food. It plays a vital role as a building block of coenzyme A, which is involved in many essential bodily functions.

Pantothenic Acid: Energy for Body and Mind

Vitamin B5 plays a key role in many processes throughout the body. One of its most important functions is turning the food we eat into energy. Pantothenic acid helps the body metabolise carbs, fats, proteins, and amino acids, turning them into fuel. But that’s not all – it also supports:

  • Protein, carbohydrate, and fat metabolism
  • Growth
  • Strengthening the nervous system
  • Mental performance
  • Wound healing
  • Hair pigmentation
  • The maintenance of bones, teeth, hair, and nails
  • Immune function
  • The production of cholesterol, provitamin D, bile acids, and amino acids for cell membrane construction
  • The formation of neurotransmitters, vitamin D, and steroid hormones (like oestrogen, testosterone, and cortisol)

Several studies are also looking into whether Pantothenic acid could help combat dementia caused by Alzheimer’s disease.

How Much Pantothenic Acid Do I Need?

The German Nutrition Society (DGE) and the European Food Safety Authority (EFSA) recommend the following daily intake of Vitamin B5:

  • Infants (0-1 year): 2-3 mg
  • Children (1-18 years): 4-5 mg
  • Adults: 5 mg

Since excess Pantothenic acid is excreted through urine, overdosing is rare. In extreme cases, very high levels of Vitamin B5 may cause mild digestive issues like diarrhoea.

Foods High in Pantothenic Acid: The Best Sources of Vitamin B5

Pantothenic acid is found in a wide variety of foods—which makes sense, given that its name comes from the Greek word "pantos", meaning "everywhere". Here are some of the best sources:

  • Pork and beef offal
  • Yeast, especially brewer’s yeast
  • Eggs
  • Porcini, button and shiitake mushrooms
  • Soybeans and lentils
  • Walnuts and hazelnuts
  • Unpolished rice
  • Cashews
  • Avocado
  • Cauliflower and broccoli
  • Cow’s milk
  • Fish and seafood, especially salmon and herring
  • Oats
  • Spelt flour
  • Soy sprouts

Other foods rich in pantothenic acid include whole grains, muscle meat, poultry, potatoes, tomatoes, and sunflower seeds.

When preparing foods high in pantothenic acid, remember that it’s water-soluble and sensitive to heat. So, cooking in water or at high temperatures can lead to significant nutrient loss. Whenever possible, eat these foods raw or cook them gently.

How Can I Recognise a Pantothenic Acid Deficiency?

In healthy people with a balanced diet, a pantothenic acid deficiency is rare. It typically only occurs in cases of highly unbalanced diets. Common symptoms of a deficiency include:

  • Sleep disturbances
  • Headaches
  • Weakened immune system
  • Persistent fatigue
  • Stress intolerance
  • Burning Feet Syndrome (tingling, numbness, or burning sensations in the feet)
  • Muscle cramps
  • Digestive issues
  • Depression
  • Poor wound healing

If you notice any of these symptoms, it’s a good idea to speak to your doctor. People with diabetes, high alcohol intake, or chronic illnesses should pay special attention to their vitamin B5 intake.

Article Sources

Deutsche Gesellschaft für Ernährung e. V. (DGE): Pantothensäure, 2021
https://www.dge.de/wissenschaft/referenzwerte/pantothensaeure/#:~:text=Pantothens%C3%A4ure%20ist%20beteiligt%20am%20Aufbau,zu%20den%20B%2DVitaminen%20geh%C3%B6rt.

Deutsche Gesellschaft für Ernährung e. V. (DGE): Ausgewählte Fragen und Antworten zu Pantothensäure
https://www.dge.de/gesunde-ernaehrung/faq/ausgewaehlte-fragen-und-antworten-zu-pantothensaeure/

Gesundheit.GV.AT, Öffentliches Gesundheitsportal Österreichs: Pantothensäure
https://www.gesundheit.gv.at/leben/ernaehrung/vitamine-mineralstoffe/wasserloesliche-vitamine/pantothensaeure.html

Bundeszentrum für Ernährung: Ballaststoffe, Magnesium, Pantothensäure
https://www.bzfe.de/service/news/aktuelle-meldungen/news-archiv/meldungen-2021/dezemer/ballaststoffe-magnesium-pantothensaeure/#:~:text=F%C3%BCr%20Pantothens%C3%A4ure%20wird%20ein%20Sch%C3%A4tzwert,vollwertige%20Ern%C3%A4hrung%20gut%20zu%20erreichen.

European Food Safety Authority: Scientific Opinion on the substantiation of Health claims related to pantothenic acid and energy-yielding metabolism, mental performance, mantenance of bone, maintenance of teeth, maintenance of hair, maintenance of skin, maintenance of nails and synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters, 2009
https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2009.1218

Peter Kreuzaler, Paolo Inglese, Avinash Ghanate u. a.: Vitamin B5 supports MYC concogenic metabolism and tumor progression in breast cancer, in: Nature Metabolism, 2023
https://www.nature.com/articles/s42255-023-00915-7

A. G. Tahiliani, C. J. Beinlich: Pantothenic acid in health and desease, in: ScienceDirect, 1991
https://www.sciencedirect.com/science/article/abs/pii/S0083672908606846?via%3Dihub

Jingshu Xu, Stefano Patassini, Paul Begley u. a.: Cerebral deficiency of vitamin B5 (D-Pantothenic acid; pantothenate) as a potentially-reversible cause of neurodegeneration and dementia in sporadic Alzheimer's desease, in: ScienceDirect, 2020
https://www.sciencedirect.com/science/article/pii/S0006291X20309190?via%3Dihub

National Institutes of Health, USA: Pantothenic Acid, 2021
https://ods.od.nih.gov/factsheets/PantothenicAcid-HealthProfessional/

Cunzhen Zhao, Ziweis Wen, Yunfei Gao u. a.: Pantothenic Acid Alleviates Fat Deposition and Inflammation by Suppressing the JNK/P38 MAPK Signaling Pathway, in: Journal of Medicinal Food, 2024
https://www.liebertpub.com/doi/abs/10.1089/jmf.2023.k.0292

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Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Do not exceed the indicated daily intake. Keep out of reach of children. Please inform and consult your doctor before consuming this product. Not suitable for children and adolescents under 18 years, pregnant or breastfeeding women. Refrain from taking other food supplements containing zinc. Persons taking anticoagulant medication should seek medical advice before consuming vitamin K-containing supplements.

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↡ Ongoing survey of 3,000+ AG1 customers after 12+ days of use.

§ In a third-party, observational study conducted on 35 healthy adults ages 25-48 assessing the self-perceived efficacy of AG1 over the course of 3 months. The study was conducted on a similar version of AG1's continually evolving formulation. The study results are transferable because of comparable ingredients and amounts.

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⬥ AG1 single subscriptions price and dose-matched average aggregated prices in 9 individual nutritional supplement categories with comparable ingredients. The prices of the individual supplements are the average prices of three individual products available online for each compared category, each with comparable ingredients. To ensure a fair basis for comparison, where the comparison products have different dosages, the prices were mathematically adjusted to correspond to the dosage contained in AG1. The 9 compared categories are vitamin B12, folate (Methylfolate), vitamin C, vitamin E, bacterial cultures, zinc, coenzyme Q10, greens powder and fibre.

Research Studies
a. In a triple-blind, randomised, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks.
b. In a double-blind, randomised, placebo-controlled 2-week cross-over clinical trial assessing microbiome shifts in 20 active adults ages 19-37.
c. In a double-blind, randomised, placebo-controlled 2-week cross-over clinical trial assessing microbiome shifts of 24 healthy adults with occasional GI distress ages 26-59.
d. In a double-blind, randomised, placebo-controlled cross-over clinical trial assessing bioavailability in 16 healthy adults ages 18-42 over the course of 8 hours.
The studies were conducted on a similar version of AG1's continually evolving formulation. The transferability of the study results is ensured because of comparable ingredients and amounts.

◊ Key health benefits:

(1) Immune system: With vitamins A, C, B6 and B12 as well as folate, zinc, copper and selenium, AG1 contributes to the normal function of the immune system. Vitamin C contributes to maintain the normal function of the immune system during and after intense physical exercise. 200 mg Vitamin C taken daily in addition to the recommended daily dose (80 mg) contributes to the normal function of the immune system during and after intensive physical activity.

(2) Energy levels: Vitamins C, B6, B12, riboflavin, niacin, pantothenic acid and magnesium contribute to normal energy-yielding metabolism and to the reduction of tiredness and fatigue. Magnesium contributes to electrolyte balance. Biotin, zinc and chromium contribute to normal macronutrient metabolism.

(3) Digestion: Calcium contributes to the normal function of digestive enzymes. With vitamin A, biotin, riboflavin and niacin, AG1 contributes to the maintenance of normal mucous membranes (e.g. intestinal mucosa).

(4) Focus; Mental performance; Psychological function; Nervous system: With pantothenic acid, AG1 contributes to normal mental performance. Zinc contributes to normal cognitive function. With vitamins C, B6, B12, B1, B3 and B7 AG1 contributes to normal psychological function and to normal functioning of the nervous system. Calcium contributes to normal neurotransmission.

‡ Additional health benefits:

(5) Muscles: With calcium and magnesium, AG1 contributes to normal muscle function.

(6) Cell Protection: With vitamins E and C as well as riboflavin, zinc, copper and selenium, AG1 contributes to the protection of cells from oxidative stress. Phosphorus contributes to normal function of cell membranes. Folate, Vitamin B6 and B12 contribute to normal homocysteine metabolism.

(7) Skin, hair & nails: With vitamins A, as well as riboflavin, niacin, biotin and zinc, AG1 contributes to the maintenance of normal skin. Vitamin C contributes to normal collagen formation for the normal function of skin. Copper contributes to normal connective tissue. Vitamin B7, zinc and selenium contribute to the maintenance of normal hair. Zinc and selenium contribute to the maintenance of normal nails.

(8) Hormonal system: With vitamin B6, AG1 contributes to the regulation of hormonal activity. Zinc contributes to the maintenance of normal testosterone levels in the blood. Selenium contributes to the normal thyroid function. With chromium, AG1 contributes to the maintenance of normal blood glucose levels.

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