RESEARCH STUDIES
Our innovation is driven by our ongoing investments in research and clinical discovery. We ensure the benefits of our products are thoroughly researched and any claims are substantiated by multiple bodies of research on ingredients and the finished formula. The impact of AG1 Next Gen is not just experienced, it's measurable.*1-4
AG1 Next Gen has been put to the test in multiple gold-standard clinical trials, consistently showing its efficacy in closing nutrient gaps and supporting gut health across diverse populations and study designs.*1-4
AG1 Next Gen has been put to the test in multiple gold-standard clinical trials, consistently showing its efficacy in closing nutrient gaps and supporting gut health across diverse populations and study designs.*1-4
WHY THIS MATTERS
In four randomized, placebo-controlled trials—meeting strict and widely accepted standards for clinical research—AG1 Next Gen demonstrated a statistically significant and positive impact on closing common nutrient gaps. These studies included participants with diverse diets, backgrounds, ages, and activity levels.¹⁻⁴
in
subjects drinking AG1 Next Gen had an increase in RBC folate.1
WHY THIS MATTERS
Adequate micronutrients are needed to support the body in the production of energy, building proteins, and metabolizing food. They act as co-factors and individual building blocks. Maintaining consistent intake is key for overall health.*
increase in Vitamin C levels1
WHY THIS MATTERS
Vitamin C supports the body's ability to combat oxidative stress and support immune defenses. It is a super antioxidant that plays a fundamental role in various physical and cellular processes.*
Over
Average increase in healthy bacteria in the gut1-3
WHY THIS MATTERS
Beneficial bacteria—such as the probiotic strains in AG1 Next Gen—are important for maintaining a healthy microbiome and play a key role in supporting overall gut health.*
Folate levels were significantly increased within 30 minutes of drinking AG1 Next Gen.4
WHY THIS MATTERS
AG1 Next Gen delivers key nutrients like folate, vitamin C, and zinc—in bioavailable forms the body can easily and readily utilize, maximizing their potential benefits.*
1 Triple-blind, randomized, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks.
2 Double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome shifts in 20 active adults ages 19-37.
3 Double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome assessments of 24 healthy adults with occasional GI distress ages 26-59.
4 Double-blind, randomized, placebo-controlled crossover clinical trial assessing nutrient gaps and bioavailability in 16 healthy adults ages 18-42 over the course of 8 hours.
There are many ways to study how nutrition impacts the body. In our clinical research, we use advanced tools and technologies—alongside our academic and clinical partners—to explore the connection between nutrient intake and microbiome composition.
Our in-house team of clinicians, scientists, and formulators brings diverse expertise across nutrition, metabolism, microbiome, food science, and related fields. We also collaborate with independent experts, academic institutions, and clinical partners to advance research and expand our understanding with cutting-edge technology.
OUR ADVISORS
Our independent Science and Innovation Advisors bring deep expertise across nutrition science, health, and research. They work alongside our in-house team to provide guidance on research and product development, helping to ensure our work remains rigorous, forward-looking, and grounded in evidence.
We’re proud to share that four clinical studies – rigorously designed, randomized, placebo-controlled trials – on the AG1 Next Gen formula have been completed. This is a major milestone in our scientific journey and one that underscores our long-standing commitment to evidence-based innovation.
Just like the trials themselves, the clinical research lifecycle is also rigorous, and it can be lengthy. Here’s a bit more about what we’ve done and where we stand.
