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How AG1 Supports Immune Health: Key Nutrients, Ingredients, and Science

A closeup magnifying glass on a bottle of AG1 with green color on the greens powder

How AG1 Supports Immune Health: Key Nutrients, Ingredients, and Science

Reviewed By: Caitlyn Edwards, PhD, RD, Senior Research Scientist, Research

4 MIN READ — 4 Citations — 05/29/2026

Supporting your immune system starts with giving your body the nutrients it needs every day. AG1 Next Gen combines essential vitamins, minerals, superfoods, and probiotics to help fill common nutrient gaps and support overall immune health.

Key Takeaways

01.
Drinking AG1 Next Gen daily provides vitamins and minerals to support your body's immune system and overall wellness.
02.
Its clinically studied formula combines essential nutrients, superfoods for immune support, and probiotics designed to support immune resilience year-round.
03.
AG1 helps address common nutrient gaps—even in healthy eaters—by complementing your day-to-day diet with foundational nutrition.
04.
Research has shown improvements in key nutrient levels and beneficial gut bacteria within months of consistent use of AG1 Next Gen.^1,2
05.
As a once-daily immune support supplement, AG1 supports immune health, gut health, and whole-body vitality.

What is AG1?

AG1 Next Gen is a research-backed daily health drink providing comprehensive nutrition in one serving. Our clinically studied formula contains more than 75 vitamins, minerals, and whole-food-sourced nutrients; it’s a foundational nutrition supplement designed to help you feel vital and nourished. We did the formulating (to get you a daily dose of essential nutrients—you just do the mixing.

One scoop once a day provides multiple benefits to support your baseline wellbeing, starting by helping fill common nutrient gaps. It’s an excellent way to supplement your diet to support your overall health.*

Key ingredients for immune support

Thinking about taking AG1 for immune health?

You should always take a food-first approach to nutrition, but even healthy eaters can experience nutrient gaps due to differences in diet and food quality, genetics, gut health, and nutrient bioavailability. In an analysis of 157 participants across four clinical trials, 87% had at least one dietary nutrient gap, and most had four or more. AG1 Next Gen has been shown to help fill common nutritional gaps and complement participants’ day-to-day diets.

Here’s what’s in AG1:

A daily dose of essential nutrients intended to support your body’s immune defense and keep you resilient, day in and day out
Vitamin C and zinc to support immune health
Superfoods and functional mushrooms for added whole food nutrients; these aid in filling nutrient gaps and replenishing a range of phytonutrients, promoting whole body health
Probiotics, which promote gut health and immune function³

The combination of these nutrients, superfoods, and probiotics helps support the systems your body relies on to stay healthy and resilient. Consider AG1 a gentle way to help your immune system by ensuring it has the fuel and support it needs to function.*

AG1 Next Gen is well-researched

Most supplements aren’t clinically studied. AG1 Next Gen is different.

Our formula is shown to support your body’s various systems. It’s a low-effort, yet comprehensive way to get your body important vitamins, minerals, and probiotics—every day.

Our team has an ongoing commitment to discovery research, ensuring the benefits of our products are actually measurable. A few examples:

7 in 10 study participants had an increase in RBC folate, a 33% increase in Vitamin C levels after 3 months, and an average of over 10x increase in healthy bacteria in the gut.⁴
After drinking AG1 Next Gen in addition to a healthy diet, study participants showed 94% of nutrient requirements met, as compared to only 71% of requirements met with diet alone.⁴

Visit our Research Hub for more information about our clinical studies, our research team, and the results you can expect.

It’s essential to note that a drink of AG1 Next Gen is not a replacement for consistent consumption of the healthy, nutritious food your body requires. All studied improvements complement a healthy, nutrient-dense diet and other healthy habits.

How to incorporate AG1 into your daily routine

This one’s easy. It’s just one scoop, once a day. We recommend taking it first thing in the morning, but the timing can be flexible—just make it work for you so you can stick to it.

How to enjoy AG1:

Add AG1 to your first glass of water in the morning.
Mix it into a smoothie or add it to a protein shake.
Enjoy it with lunch.
Drink it before, during, or after a workout—though it’s not a protein shake or a traditional pre-workout fuel beverage.

As an all-in-one immune supplement, AG1 offers a convenient, once-daily way to help support immune health, gut health, and whole-body vitality—making it easier to build a strong nutritional foundation alongside a balanced diet and healthy lifestyle.

References:

Gonzalez AM, et al. AG1®, a foundational nutrition supplement, closes nutrient gaps in healthy resistance-trained adults. J Int Soc Sports Nutr. 2025; published online. doi:10.1080/15502783.2025.2550174
La Monica MB, Raub B, Hartshorn S, Gustat AL, Grdic J, Kirby TO, Townsend JR, Sandrock J, Ziegenfuss TN. The effects of AG1® supplementation on the gut microbiome of healthy adults: a randomized, double-blind, placebo-controlled clinical trial. J Int Soc Sports Nutr. 2024;21(1):2409682. doi:10.1080/15502783.2024.2409682
Wiertsema SP, van Bergenhenegouwen J, Garssen J, Knippels LMJ. The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies. Nutrients. 2021;13(3):886. Published 2021 Mar 9. doi:10.3390/nu13030886
In a triple-blind, randomized, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks.