Home
Ingredients
Folate (as 5-MTHF) Facts

Folate supplement powder, an active, bioavailable form of vitamin B9

Folate (as 5-MTHF) Facts

Folate is a water-soluble B-vitamin (B9) that naturally occurs in leafy greens, legumes, and certain fruits like oranges. In the body folate functions as a coenzyme in critical metabolic processes, especially those involving DNA synthesis, cell division, and amino acid metabolism.

Key Benefits of Folate (as 5-MTHF):

Folate is involved in several processes in the body including:

DNA and RNA synthesis – Essential for new cell formation and growth.
Methylation cycle – Provides methyl groups that regulate neurotransmitter production.
Amino acid metabolism – Helps process homocysteine, supporting cardiovascular health.
Red blood cell support – Plays a role in the formation of healthy blood cells.
Nervous system support – Works with other B vitamins to maintain cognitive function and neurological balance.

Why it Matters:

Folate is necessary for life at every stage, but it is especially important during times of growth and renewal. Because dietary intake is sometimes insufficient and folate is not stored in large amounts in the body, supplementation can help ensure consistent support for energy, cognition, cardiovascular function, and overall health.
Natural folate content in foods can be lost during cooking, making fortified sources and supplementation important.
The folate used by AG1 is methylated (5-MTHF) and is found to be more bioavailable than folic acid.Because folate metabolism varies between individuals, supplementing with 5-MTHF ensures your body receives folate in a form it can use immediately. It is particularly important for populations with higher needs, such as women of childbearing age, or for those whose bodies may not efficiently convert folic acid.