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Phosphatidylserine Facts

Phosphatidylserine is a naturally occurring phospholipid or type of fat that is a key structural component of all cell membranes, especially in the brain. It plays a role in helping to maintain cell fluidity and integrity, ensuring that nutrients can enter cells efficiently and waste products can be removed.

Key Benefits of Phosphatidylserine:

  • Supports cognitive function
  • Helps maintain cellular integrity and function

Why it Matters:

Every cell in the human body contains phospholipids. By strengthening cell membranes, phospholipids promote resilience at every level of the body. More specifically, they support normal brain, liver and nerve function by maintaining membrane integrity and signaling ¹.

Citations:

1. Choudhary D, Bhattacharyya S, Joshi K. Body weight management in adults under chronic stress through treatment with ashwagandha root extract. J Evid Based Complement Altern Med. 2017;22(1):96-106. doi:10.1177/2156587216641830 [See also Choudhary 2024 for phosphatidylserine data]

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  1. In a triple-blind, randomized, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks using the AG1 Next Gen formula.
  2. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome shifts in 20 active adults ages 19-37 using the AG1 Next Gen formula.
  3. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome assessments of 40 healthy adults with occasional GI distress ages 26-59 over the course of 4 weeks using the AG1 Next Gen formula.
  4. In a double-blind, randomized, placebo-controlled crossover clinical trial assessing nutrient gaps and bioavailability in 16 healthy adults ages 18-42 over the course of 8 hours using the AG1 Next Gen formula.
  5. In a third-party, single-arm, closed label interventional study of 104 healthy adults ages 25-59 assessing self-perceived efficacy of AG1 Next Gen over 3 months.

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