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Zinc citrate supplement, a highly bioavailable form of zinc mineral

Zinc (as zinc citrate) Facts

Zinc is an essential mineral that is essential for the function of over 300 enzymes. It supports immune defenses, cell growth, and metabolism ¹ It's also involved in several metabolic pathways in the body, including mood regulation. Zinc citrate is a well-absorbed, gentle version of zinc that helps the body use this mineral efficiently.

Key Benefits of Zinc (as zinc citrate):

  • Contributes to normal immune function.
  • Supports normal skin integrity.
  • Required for DNA synthesis and cell division.
  • Contributes to normal reproductive function.
  • Supports the nervous system for a healthy mood

Why it Matters:

Zinc is a critical nutrient required daily, but the body does not store it in significant amounts—meaning a consistent dietary source is necessary.

Phytates in some plant foods can reduce zinc absorption; individuals with limited animal-source foods may have lower zinc bioavailability.

Both acute and chronic stress—including periods of intense physical activity—can deplete zinc levels, creating a cycle where stress reduces zinc stores, and low zinc in turn impairs the body's ability to cope with stress ²

Citations:

1. National Institutes of Health, Office of Dietary Supplements (NIH ODS). Zinc: fact sheet for health professionals. https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional
2. Azargoonjahromi A. Current evidence on the association of zinc ... . Nutr Rev. 2024;82(3):291-303. doi:10.1093/nutrit/nuad058
3. Córdova A, Alvarez-Mon M. Behaviour of zinc in physical exercise: a special reference to immunity and fatigue. Neurosci Biobehav Rev. 1995;19(3):439-445. doi:10.1016/0149-7634(94)00054-g

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ā—ŠAccording to IQVIA Pro Voice Survey of 248 primary care physicians in December 2025.

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  1. In a triple-blind, randomized, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks using the AG1 Next Gen formula.
  2. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome shifts in 20 active adults ages 19-37 using the AG1 Next Gen formula.
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  4. In a double-blind, randomized, placebo-controlled crossover clinical trial assessing nutrient gaps and bioavailability in 16 healthy adults ages 18-42 over the course of 8 hours using the AG1 Next Gen formula.
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