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Best Drinks and Juices for Immune Function: Nutrients That Support Defense
Wondering which drinks provide the best immune support? We compare the top juices and fermented beverages, as well as supplements that can provide additional support.
Key Takeaways
- 01.
Drinks rich in vitamins A, D, E, C, B-complex, zinc, selenium, and iron support the normal function of immune cells and barriers like skin and the gut lining.
- 02.
Fermented drinks supply probiotics for gut health, functional juices and teas can offer antioxidants, and supplement powders or wellness shots can deliver targeted nutrients conveniently.
- 03.
Use vitamin C to enhance iron absorption, avoid nutrient interference, and include prebiotic fiber to maximize gut health.
We’re all familiar with the advice to “drink plenty of fluids” when you’re feeling run-down. While hydration is essential for supporting immune function, do some drinks support the immune system more than others? From fruit juices and probiotic drinks to supplement powders and wellness shots, the list of immune drink choices is long. Determining which options deliver the most nutritional value isn’t always easy. In this guide, we compare which drinks provide the best immune support and give you tips for maximizing their benefits.
What drinks are good for immune support?
Immune-boosting drinks vary widely in their composition and benefits, with different categories promising various benefits. While no drink can enhance immune function beyond the body’s natural capacity, adequate nutrient intake supports normal immune function.
- Fruit juices can provide vitamins, minerals, and antioxidants.
- Fermented drinks like kombucha and kefir deliver probiotics to promote gut microbiome diversity.
- Wellness shots can supply a concentrated amount of spices or botanicals with antioxidant properties, such as ginger and turmeric.
- Supplements like effervescent powders can deliver concentrated doses of one or a few nutrients, while foundational nutrition supplements provide a much wider range of ingredients formulated for immune support.
Key ingredients for immune support
When you’re shopping for an immune-boosting juice or other drink, look for those with a high percentage of your recommended daily value (DV) for the following vitamins and minerals.
Fat-soluble vitamins
Vitamins A, D, and E play roles in how immune cells become specialized for a particular job and move about the body.
Vitamin A supports the structure and function of primary barriers like the skin and respiratory tract.1 It also supports the normal development and function of T and B cells.2
Vitamin D supports the production of proteins that are part of the body’s natural defense system.3
Vitamin E is an antioxidant that helps protect cell walls in barrier tissue from environmental stress.4
Water-soluble vitamins
For many people, vitamin C is the go-to immune booster when they want extra immune support—and for good reason. Vitamin C supports the function of innate immune cells, helping them respond to stressors, while protecting them from damage.5 6
B vitamins, including B6, B12, and folate (B9), support immune cell function in the GI tract.7
Essential trace minerals
Zinc, selenium, and iron provide the structural and communications support required for immune health. Zinc is a cofactor for over 300 enzymes, supporting the growth and differentiation of immune cells.8 9 Selenium is incorporated into “selenoproteins” that support antioxidant defenses and help regulate the immune response.10
Top immune drinks to consider
From fermented beverages to functional juices and wellness shots, these immune drinks offer a range of nutrients and bioactive compounds that support your body’s natural defense system.
Fermented and probiotic beverages
The GI tract is one of the immune system’s key hubs. It’s also home to trillions of microbes, including “good bacteria” that help educate the immune system to distinguish between harmful invaders and your own cells.11 The gut microbiome also helps maintain balance and support the integrity of the gut lining.12
Fermented drinks like kefir and kombucha contain live bacteria that support a more diverse and effective microbial community.13 Kombucha also contains tea-derived polyphenols, potent antioxidants.14 Look for products labeled with ‘live cultures’ to ensure probiotic content.
Botanical and herbal infusions
Tea and herbal infusions often make excellent antioxidant drinks. Green tea and matcha contain catechins, antioxidant polyphenols that have also been shown to support immune cell function.15 Elderberry, echinacea, and ginger teas are also good sources of antioxidants.16,17,18
Functional juices
In addition to its many nutrients, beetroot juice contains antioxidants as well as dietary nitrates that support healthy blood flow.19
Orange juice is an immune support staple with its vitamin C and folate content, but tomato juice is an often-overlooked alternative that also provides magnesium and lycopene, an antioxidant.20
Supplement powders and wellness shots
While there’s no substitute for juices and whole foods, supplements can help fill common nutrient gaps. There are many drinkable powders available that provide a convenient dose of vitamins—typically vitamin C, though they sometimes also include B vitamins or small amounts of zinc.
Wellness shots are small-volume, high-concentration drinks that usually feature bioactive spices like ginger or turmeric. Both of these contain antioxidants, while ginger has also been studied for its anti-nausea and pain relief properties.21,22
How to incorporate immune drinks into your routine
How you consume drinks for immune support can affect how much benefit you get from them.
Use vitamin C to unlock iron.
When drinking veggie juice (which usually contains plant-based iron), add a squeeze of lemon. Vitamin C changes the “chemical shape” of iron for easier absorption.23
Avoid nutrient “traffic jams.”
High doses of calcium or iron can block the absorption of zinc.24 Try to consume zinc-fortified drinks separately from dairy-heavy meals or iron supplements.
Don’t forget prebiotics.
If you’re relying on fruit juice for immune support nutrients, look for options with pulp. When making smoothies, blend whole fruits and vegetables and add chia or flaxseeds. Prebiotic sodas are also available. These strategies ensure that probiotic drinks like kombucha are paired with complementary dietary fiber that feeds healthy gut bacteria.
Consider a foundational nutrition supplement
Juices can provide a variety of essential vitamins, minerals, and antioxidants to complement a diet of nutrient-rich whole foods, and fermented drinks can supply probiotics for additional support. Popular powder supplements can help fill common nutrient gaps by providing a boost of a few targeted nutrients. A foundational nutrition supplement like AG1, on the other hand, addresses multiple nutrient gaps at once.
AG1 combines over 75 vitamins, minerals, and whole-food-sourced ingredients, including prebiotics and probiotics that promote a healthy gut and support immune defense. Unlike a one-time immunity shot, AG1 is designed to be a daily habit that helps fill common nutrient gaps and supports whole body health—including immune health.25
References:
- Biesalski HK. Biochemical, morphological, and functional aspects of systemic and local vitamin A deficiency in the respiratory tract. Ann N Y Acad Sci. 1992;669:325-331. doi:10.1111/j.1749-6632.1992.tb17115.x
- Iwata M, Hirakiyama A, Eshima Y, Kagechika H, Kato C, Song SY. Retinoic acid imprints gut-homing specificity on T cells. Immunity. 2004;21(4):527-538. doi:10.1016/j.immuni.2004.08.011
- White JH. Emerging Roles of Vitamin D-Induced Antimicrobial Peptides in Antiviral Innate Immunity. Nutrients. 2022;14(2):284. doi:10.3390/nu14020284
- Traber MG, Atkinson J. Vitamin E, antioxidant and nothing more. Free Radic Biol Med. 2007;43(1):4-15. doi:10.1016/j.freeradbiomed.2007.03.024
- Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017;9(11):1211. doi:10.3390/nu9111211
- Hemilä H, Chalker E. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev. 2013;2013(1):CD000980. doi:10.1002/14651858.CD000980.pub4
- Hossain KS, Amarasena S, Mayengbam S. B Vitamins and Their Roles in Gut Health. Microorganisms. 2022;10(6):1168. doi:10.3390/microorganisms10061168
- Hojyo S, Fukada T. Roles of Zinc Signaling in the Immune System. J Immunol Res. 2016;2016:6762343. doi:10.1155/2016/6762343
- Hemilä H. Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. JRSM Open. 2017;8(5):2054270417694291. doi:10.1177/2054270417694291
- Avery JC, Hoffmann PR. Selenium, Selenoproteins, and Immunity. Nutrients. 2018;10(9):1203. doi:10.3390/nu10091203
- Zhao Q, Elson CO. Adaptive immune education by gut microbiota antigens. Immunology. 2018;154(1):28-37. doi:10.1111/imm.12896
- La Flamme AC, Milling S. Immunological partners: the gut microbiome in homeostasis and disease. Immunology. 2020;161(1):1-3. doi:10.1111/imm.13247
- Choi Y, Keum GB, Kang J, et al. Evaluation of kefir consumption on gut microbial diversity in a healthy young population using full-length 16S rRNA sequencing. Front Microbiol. 2025;16:1587831. doi:10.3389/fmicb.2025.1587831
- Cardoso RR, Neto RO, Dos Santos D’Almeida CT, et al. Kombuchas from green and black teas have different phenolic profile, which impacts their antioxidant capacities, antibacterial and antiproliferative activities. Food Res Int. 2020;128:108782. doi:10.1016/j.foodres.2019.108782
- Xu J, Xu Z, Zheng W. A Review of the Antiviral Role of Green Tea Catechins. Molecules. 2017;22(8):1337. doi:10.3390/molecules22081337
- Osman AG, Avula B, Katragunta K, Ali Z, Chittiboyina AG, Khan IA. Elderberry Extracts: Characterization of the Polyphenolic Chemical Composition, Quality Consistency, Safety, Adulteration, and Attenuation of Oxidative Stress- and Inflammation-Induced Stress. Molecules. 2023;28(7):3148. doi:10.3390/molecules28073148
- Viapiana A, Wesolowski M. The Phenolic Contents and Antioxidant Activities of Infusions of Sambucus nigra L. Plant Foods Hum Nutr. 2017;72(1):82-87. doi:10.1007/s11130-016-0594-x
- Stephen Adeyemi O, Emmanuel Rotimi D, Demilade Fatinukun H, et al. Antioxidant and inflammatory-modulating properties of ginger and bitterleaf teas. Int J Environ Health Res. 2024;34(12):4122-4136. doi:10.1080/09603123.2024.2338894
- Hamby M, Speed J, Islam T, Barr E, Hildebrandt E, do Carmo J, Drummond H. 4-weeks of daily nitrate-rich beetroot juice consumption augments cerebral autoregulation in older adults [abstract]. Physiology. 2025;40(S1):0423. doi:10.1152/physiol.2025.40.S1.0423
- Jacob K, Periago MJ, Böhm V, Berruezo GR. Influence of lycopene and vitamin C from tomato juice on biomarkers of oxidative stress and inflammation. British Journal of Nutrition. 2008;99(1):137-146. doi:10.1017/S0007114507791894
- Ballester P, Cerdá B, Arcusa R, García-Muñoz AM, Marhuenda J, Zafrilla P. Antioxidant Activity in Extracts from Zingiberaceae Family: Cardamom, Turmeric, and Ginger. Molecules. 2023;28(10):4024. doi:10.3390/molecules28104024
- Li H, Liu Y, Luo D, et al. Ginger for health care: An overview of systematic reviews. Complement Ther Med. 2019;45:114-123. doi:10.1016/j.ctim.2019.06.002
- Cook JD, Reddy MB. Effect of ascorbic acid intake on nonheme-iron absorption from a complete diet. Am J Clin Nutr. 2001;73(1):93-98. doi:10.1093/ajcn/73.1.93
- Solomons NW. Competitive interaction of iron and zinc in the diet: consequences for human nutrition. J Nutr. 1986;116(6):927-935. doi:10.1093/jn/116.6.927
- Based on clinical studies in healthy adults ages 18–59, evaluating nutrient biomarkers, microbiome shifts, and bioavailability. Study designs and durations varied. For more information, visit drinkag1.com/science