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Fresh pineapple cross-section, natural source of bromelain enzyme

Bromelain Facts

Bromelain is a natural proteolytic enzyme extracted from the stem and fruit of the pineapple (Ananas comosus). It helps break down proteins into smaller peptides and amino acids, supporting digestion and nutrient utilization. Bromelain has also been studied for its role in maintaining tissue comfort and supporting the body’s natural recovery processes.

Key Benefits of Bromelain:

  • Enhances nutrient utilization by improving protein absorption and availability.
  • Supports protein digestion, nutrient utilization, and helps maintain normal tissue comfort.

Why it Matters:

Up to 70 million people in the U.S. experience digestive issues each year ¹. Supporting protein digestion may ease the burden on the digestive system.
Most U.S. adults consume well above the RDA for protein ². Enzymes like bromelain can help maximize the nutritional benefit of this intake ³.
Musculoskeletal complaints are among the most common reasons for physician visits, highlighting the value of ingredients that support normal tissue recovery pathways ⁓.
Bromelain activity varies with fruit ripeness and source; standardized extracts provide consistent enzyme activity. Additionally, supplements provide higher and more reliable enzyme activity than fruit alone.

Citations:

1. National Institute of ... Digestive and Kidney ... (NIDDK). Digestive ... statistics for the United States. Updated 2023. https://www.niddk.nih.gov/health-information/health-statistics/digestive-diseases
2. Food Surveys Research Group (FSRG), USDA. Protein intakes of US adults. Dietary Brief. 2021. https://www.ars.usda.gov/nea/bhnrc/fsrg
3. Kansakar U, Trimarco V, Mone P, Varzideh F, Lombardi A, Santulli G. Choline supplements: an update. Front Endocrinol (Lausanne). 2024;14:1337344. doi:10.3389/fendo.2023.1337344
4. Dawod B, Marshall JS. Cytokines and soluble receptors in ... microenvironment. Front Immunol. 2025;16:1465892. doi:10.3389/fimmu.2025.1465892

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Information on this site is provided for informational purposes only. It is not meant to substitute for medical advice from your physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. Carefully read all product documentation. If you have or suspect that you have a medical problem, promptly contact your regular health care provider.

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ā—ŠAccording to IQVIA Pro Voice Survey of 248 primary care physicians in December 2025.

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  1. In a triple-blind, randomized, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks using the AG1 Next Gen formula.
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