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Burdock Root Extract

Burdock (Arctium lappa) is a root vegetable traditionally used in food and herbal practices. It contains inulin (a prebiotic fiber), polyphenols, and other natural compounds that support digestive health, and antioxidant defense.

Key Benefits:

  • Provides prebiotic inulin to support digestive balance and beneficial gut bacteria.
  • Provides antioxidant polyphenols.
  • Contains bitter compounds that promote digestion and support nutrient absorption

Why it Matters:

Digestive health is a widespread concern: 60–70 million Americans are affected by digestive issues annually. Nutrients that support gut balance are relevant for many adults. ¹
Fiber intake is often low: Only ~5% of U.S. adults meet recommended daily fiber intake, leaving a gap that prebiotic fibers like inulin can help address ².
Antioxidant support matters: Diets rich in antioxidant compounds are linked to healthy aging and reduced oxidative stress load, underscoring the relevance of polyphenol-containing plants like burdock ³.
Burdock is one of the few commonly eaten vegetables that naturally combines prebiotic fiber and polyphenols, giving it both digestive and antioxidant relevance.Whole burdock root contains variable levels of inulin and polyphenols; standardized extracts ensure consistent concentrations for functional formulations.

Citations:

1. National Institute of ... Digestive and Kidney ... (NIDDK). Digestive ... statistics for the United States. Updated 2023. https://www.niddk.nih.gov/health-information/health-statistics/digestive-diseases
2. Quagliani D, Felt-Gunderson P. Closing America's fiber intake gap. Am J Lifestyle Med. 2016;11(1):80-85. doi:10.1177/1559827615588079
3. Kalogerakou T, Antoniadou M. The role of dietary antioxidants, food supplements and functional foods for energy enhancement in healthcare professionals. Antioxidants (Basel). 2024;13(2):174. doi:10.3390/antiox13020174

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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ā—ŠAccording to IQVIA Pro Voice Survey of 248 primary care physicians in December 2025.

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  1. In a triple-blind, randomized, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks using the AG1 Next Gen formula.
  2. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome shifts in 20 active adults ages 19-37 using the AG1 Next Gen formula.
  3. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome assessments of 40 healthy adults with occasional GI distress ages 26-59 over the course of 4 weeks using the AG1 Next Gen formula.
  4. In a double-blind, randomized, placebo-controlled crossover clinical trial assessing nutrient gaps and bioavailability in 16 healthy adults ages 18-42 over the course of 8 hours using the AG1 Next Gen formula.
  5. In a third-party, single-arm, closed label interventional study of 104 healthy adults ages 25-59 assessing self-perceived efficacy of AG1 Next Gen over 3 months.

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