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Niacin (vitamin B3) Facts

Vitamin B3, also called niacin, is a water-soluble B-vitamin that the body uses to release energy from food and to support hundreds of biochemical reactions. It is naturally found in foods such as poultry, fish, whole grains, legumes, and some vegetables, and can also be formed in the body from the amino acid tryptophan. Because the body uses it continuously and does not store large amounts, ensuring consistent intake is important.

Key Benefits of Niacin (vitamin B3):

  • Energy metabolism ā€“ Helps convert carbohydrates, fats, and proteins into energy.
  • Antioxidant function ā€“ Contributes to maintaining the body's defense system against oxidative stress.
  • Skin and tissue health ā€“ Supports the maintenance of skin and mucous membranes.
  • Nervous system balance ā€“ Helps sustain healthy cognitive and neurological function.

Why it Matters:

About 1 in 3 adults report fatigue as a top daily concern Ā¹.

Citations:

1. American Psychological Association (APA). Stress in America 2022. Published 2022. https://www.apa.org/news/press/releases/stress

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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ā—ŠAccording to IQVIA Pro Voice Survey of 248 primary care physicians in December 2025.

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  1. In a triple-blind, randomized, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks using the AG1 Next Gen formula.
  2. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome shifts in 20 active adults ages 19-37 using the AG1 Next Gen formula.
  3. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome assessments of 40 healthy adults with occasional GI distress ages 26-59 over the course of 4 weeks using the AG1 Next Gen formula.
  4. In a double-blind, randomized, placebo-controlled crossover clinical trial assessing nutrient gaps and bioavailability in 16 healthy adults ages 18-42 over the course of 8 hours using the AG1 Next Gen formula.
  5. In a third-party, single-arm, closed label interventional study of 104 healthy adults ages 25-59 assessing self-perceived efficacy of AG1 Next Gen over 3 months.

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