1. Home
  2. Ingredients
  3. Shiitake Mushroom Facts
Fresh shiitake mushrooms with brown caps, source of shiitake mushroom powder

Shiitake Mushroom Facts

Shiitake (Lentinula edodes) is one of the most widely consumed mushrooms globally, valued for both nutrition and wellness-supportive compounds. It contains beta-glucans and polysaccharides, which have been studied for immune modulation, and eritadenine, a compound investigated for effects on lipid metabolism.

Key Benefits of Shiitake Mushrooms:

  • Supports immune health through beta-glucans that support normal immune function.
  • Provides antioxidant compounds that help protect cells from oxidative stress, contributing to healthy aging.

Why it Matters:

Oxidative stress is linked to cellular aging and everyday challenges, diets rich in antioxidants, including mushrooms, are associated with maintenance of cellular health and vitality.
Shiitake's beta-glucans work synergistically with other mushroom-derived polysaccharides (e.g., from reishi) to support immune readiness.

Citations:

1. Yang Y, Zhang H, Zhu S, et al. Ganoderma lucidum polysaccharides and immune function. Front Immunol. 2024;15:1392084. doi:10.3389/fimmu.2024.1392084

Products Included

Connect

Join Our Newsletter

Ā© 2026 AG1

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Information on this site is provided for informational purposes only. It is not meant to substitute for medical advice from your physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. Carefully read all product documentation. If you have or suspect that you have a medical problem, promptly contact your regular health care provider.

** AG1 Welcome Kit Offer valid for new AG1 subscribers only. AG1 Pro Welcome Kit included with the first AG1 Pro subscription order only. AGZ Frother Offer valid for first AGZ order only.

ā—ŠAccording to IQVIA Pro Voice Survey of 248 primary care physicians in December 2025.

ā€ ā€ Free shipping on subscription purchases for new U.S. customers only.

  1. In a triple-blind, randomized, placebo-controlled parallel-designed clinical trial evaluating nutrient biomarkers and microbiome shifts in 105 healthy adults ages 20-59 over the course of 12 weeks using the AG1 Next Gen formula.
  2. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome shifts in 20 active adults ages 19-37 using the AG1 Next Gen formula.
  3. In a double-blind, randomized, placebo-controlled 2-week crossover clinical trial assessing nutrient gaps and microbiome assessments of 40 healthy adults with occasional GI distress ages 26-59 over the course of 4 weeks using the AG1 Next Gen formula.
  4. In a double-blind, randomized, placebo-controlled crossover clinical trial assessing nutrient gaps and bioavailability in 16 healthy adults ages 18-42 over the course of 8 hours using the AG1 Next Gen formula.
  5. In a third-party, single-arm, closed label interventional study of 104 healthy adults ages 25-59 assessing self-perceived efficacy of AG1 Next Gen over 3 months.

Ī”Truemed eligibility and approval required. This link will take you to a third party website hosted by Truemed (the "Site"). Linking to this Site does not constitute an endorsement or approval by AG1 or any of its employees of the content, products, services or opinions on the Site. This is being provided as a convenience and AG1 bears no responsibility for the accuracy, legality or content of the Site or for that of any subsequent links on the Site. Contact the owners of the Site for answers to questions regarding its content.

Actual Packaging May Vary

Your privacy is our priority. Learn more:Ā Ā